论文部分内容阅读
目的:探讨血浆脑钠素(BNP)、肌钙蛋白I(CTnI)水平变化对婴幼儿肺炎心衰早期诊断的意义。方法:肺炎心衰患儿48例,分为心衰早期、心衰期、恢复期。30例健康对照组,检测各组血浆BNP及CTnI水平。结果:心衰早期患儿血浆BNP、CTnI即开始升高,心衰期达高峰。心衰早期患儿血浆BNP阳性率较CTnI阳性率有统计学差异(P<0.01)。结论:BNP、CTnI可反映心肌损伤程度,血浆BNP在心衰早期诊断方面其敏感性优于CTnI。
Objective: To investigate the significance of the changes of plasma brain natriuretic peptide (BNP) and troponin I (CTnI) in the early diagnosis of pneumonia in infants and young children. Methods: Forty-eight children with heart failure of pneumonia were divided into early heart failure, heart failure and convalescence. Thirty healthy control subjects were enrolled in this study. Plasma BNP and CTnI levels were measured in each group. Results: The plasma BNP and CTnI in the early stage of heart failure began to increase and the peak of heart rate reached its peak. The positive rate of plasma BNP in children with early heart failure was significantly higher than that of CTnI (P <0.01). Conclusion: BNP and CTnI can reflect the degree of myocardial injury. Plasma BNP is superior to CTnI in the early diagnosis of heart failure.