论文部分内容阅读
目的:探讨分析盐酸戊乙奎醚在急性有机磷中毒重度中间综合症治疗中的效果。方法:选取急性有机磷中毒并发重度中间综合症患者34例,依治疗方案分为对照组和观察组,各17例。2组患者基础治疗相同,对照组给予氯解磷定+阿托品+机械通气治疗;观察组采用氯解磷定+盐酸戊乙奎醚+机械通气治疗。观察比较2组患者肌无力症状消失时间、机械通气时间以及住院时间。结果:观察组患者肌无力症状消失时间、机械通气时间以及住院时间均明显低于对照组,经比较,差异均有统计学意义(P<0.01)。结论:盐酸戊乙奎醚可快速有效缓解急性有机磷中毒重度中间综合症患者的临床症状,显著缩短病程。
Objective: To investigate the effect of penehyclidine hydrochloride in the treatment of severe acute organophosphorus poisoning syndrome. Methods: Thirty-four patients with acute organophosphate poisoning complicated with severe intermediate syndrome were selected and divided into control group and observation group according to treatment regimen, 17 cases in each group. The patients in the two groups had the same basic treatment. The control group was treated with chlorpheniramine + atropine + mechanical ventilation. The observation group was treated with chlorpheniramine + penehyclidine hydrochloride + mechanical ventilation. Observed and compared the disappearance of muscle weakness symptoms, mechanical ventilation time and hospital stay in two groups. Results: The duration of disappearance, duration of mechanical ventilation and hospital stay in observation group were significantly lower than those in control group. The differences were statistically significant (P <0.01). Conclusion: Penehyclidine hydrochloride can quickly and effectively relieve the clinical symptoms of patients with acute severe acute organophosphorus pesticide poisoning syndrome and shorten the course of disease significantly.