丙型肝炎病毒(HCV)感染者呈世界性分布,近年发现HCV感染不但可能感染肝细胞,也可以侵入肝外多种组织和器官,而出现许多肝外相关的疾病。本文对近年来HCV感染的肝外表现作一综述,以引起国内同道们的注意。1 HCV感染性糖尿病国外一项流行病学调查研究发现:慢性丙型肝炎(HCV)患者的糖尿病发病率明显高于其它肝炎病毒感染性慢性肝病者,HCV-CAH的糖尿病发病率达25.5％,HCV性肝硬化时可达38％(对照HBV感染组仅7.8％～12％)。有研究者统计HCV性慢性肝病时糖尿病发病率可达HBV感染组的10倍以上。HCV性 Hepatitis C virus (HCV) infection is worldwide distribution, in recent years found that HCV infection may not only infect liver cells, but also can invade a variety of tissues and organs outside the liver, and there are many extrahepatic related diseases. This article reviews the extrahepatic manifestations of HCV infection in recent years to arouse the attention of domestic fellow. 1 HCV Infectious Diabetes A foreign epidemiological study found that: the incidence of diabetes in patients with chronic hepatitis C (HCV) was significantly higher than those of other hepatitis virus-infected chronic liver disease, HCV-CAH incidence of diabetes reached 25.5% Up to 38% of HCV cirrhosis (7.8% to 12% in control HBV infection group). Researchers statistics of HCV chronic liver disease incidence of diabetes up to 10 times more than HBV infection. HCV sex