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目的了解2011年郑州市手足口病流行特征以及病原构成。方法利用2011年疾病监测信息系统报告的手足口病例,对其流行病学特征进行分析。结果 2011年郑州市报告手足口病例为5 729例,重症409例,死亡9例。发病率为66.42/10万,病例主要集中在5岁及以下儿童,占发病总数的94.44%,1岁组儿童发病率最高,重症和死亡病例集中在低年龄组儿童的特点更为明显。0岁组儿童发生重症的比例和病死率最高,随着年龄增加各年龄组重症比例和病死率依次降低。不同类型病例的病原构成存在差异,相对于普通病例、重症病例和死亡病例肠道病毒EV71型检测阳性的比值比为6.64。结论 5岁及以下儿童是发病主要人群,年龄越小发生重症和死亡的风险越高,13～19 w是发病高峰,EV71为主要病原。
Objective To understand the epidemiological characteristics and pathogens of hand-foot-mouth disease in Zhengzhou in 2011. Methods The HFMD cases reported by the Disease Surveillance Information System in 2011 were used to analyze their epidemiological characteristics. Results In 2011, Zhengzhou City reported 5 729 cases of hand-foot-mouth disease, 409 severe cases and 9 deaths. The incidence was 66.42 / 100000, the cases mainly concentrated in children 5 years of age and below, accounting for 94.44% of the total incidence, the highest incidence of children in the 1-year-old group, severe and fatal cases concentrated in children with lower age group is more obvious characteristics. 0-year-old children with severe cases of the highest proportion of cases and mortality, with age increasing severity of each age group and mortality decreased in turn. Different types of cases of pathogenic constitution differences, compared with common cases, severe cases and deaths of enterovirus EV71 positive detection ratio was 6.64. Conclusions Children 5 years old and younger are the main pathogenesies. The younger the patients are, the higher the risk of serious illness and death is. The peak incidence is 13-19 w and EV71 is the main pathogen.