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目的:评价国产维库溴铵的神经肌肉阻滞效应及对心血管的影响。方法:选择择期手术病人20例,随机分为国产维库溴铵组(10例)和进口维库溴铵组(10例)。每组均注射维库溴铵0.1mg/kg后测定肌松药的起效时间和维持时间,并观察心血管反应。结果:国产维库溴铵和进口维库溴铵在神经肌肉阻滞效应的各项指标和对心血管的影响方面均无明显差异。结论:国产维库溴铵的肌松效果满意且不明显影响心血管系统。
OBJECTIVE: To evaluate the neuromuscular blockade and cardiovascular effects of domestic vecuronium. Methods: Twenty patients undergoing elective surgery were randomly divided into domestic vecuronium group (n = 10) and vecuronium group (n = 10). Each group were given vecuronium 0.1mg / kg after the onset of muscle relaxant determination of the time and maintenance, and to observe the cardiovascular response. Results: There was no significant difference in the indexes of neuromuscular blockade and cardiovascular effects between domestic vecuronium and imported vecuronium. Conclusion: The domestic vecuronium effect is satisfactory and does not affect the cardiovascular system significantly.