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对抗原的Ｔｈ１和Ｔｈ２型免疫应答可用佐剂来调节。由于所诱生的抗体同型（ＩｇＧ１和ＩｇＧ２ａ）和细胞因子可以反映在免疫应答期间所发生的Ｔｈ分化，因而作者检测了ＨＢｓＡｇ吸附于铝佐剂或同新佐剂──阳离子类脂３β－［Ｎ－（Ｎ’，Ｎ’－二甲氨基乙烷）氨甲酰］胆固
Th1 and Th2 immune responses to the antigen can be adjusted with adjuvants. Since the induced antibody isotypes (IgG1 and IgG2a) and cytokines reflect the Th differentiation that occurs during the immune response, the authors tested whether HBsAg is adsorbed to aluminum adjuvants or to the adjuvant-cationic lipids 3β- [ N- (N ’, N’-dimethylaminoethane) carbamoyl] cholestane