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本文报导,圆叶柴胡(Bupleurum rotundifolium L.)的水制剂(?)(Pecvocrine)对狗急性实验性肝炎的胆汁分泌和其化学组成的影响。试验用8只具有慢性胆囊瘘的成年狗。对胆汁进行定量(4小时),测定胆红素、胆酸盐和胆固醇的含量。给予四氯化碳4克/公斤诱发狗的急性中毒性肝炎,治疗组同时灌注(?)0.5毫克/公斤,每日一次,直至胆汁分泌完全恢复正常。 5只狗给四氯化碳,同时给予(?)治疗后,胆汁分泌在第13天(一只狗在第15天)恢复正常,胆红素在第9天,胆酸盐在第17天,胆固醇在第19天(一只狗在第21天)恢复正常。对照3只狗给四氯化碳,胆汁分泌在第17天～21天恢复正常,胆红素在第10～11
This article reports the effect of Bupleurum rotundifolium L.’s aqueous formulation Pecvocrine on bile secretion and its chemical composition in acute experimental hepatitis in dogs. Eight adult dogs with chronic gallbladder fistula were tested. The bile is quantified (4 hours) and the bilirubin, cholate and cholesterol levels are determined. Acute toxic hepatitis was induced in dogs given carbon tetrachloride at 4 g / kg. The treatment group was also infused (?) 0.5 mg / kg once daily until bile secretion returned to normal. Five dogs were given carbon tetrachloride and bile secretion returned to normal on day 13 (one dog on day 15) after treatment (?), With bilirubin on day 9 and cholate on day 17 Cholesterol returned to normal on day 19 (one dog on day 21). Control three dogs to carbon tetrachloride, bile secretion returned to normal in the first 17 days to 21 days, bilirubin in the first 10 to 11