镧系位移试剂早见报导。此类试剂中的三价金属离子的4f有空轨道,与有机分子中的带孤对电子的官能团如醇、胺、酮、硫……等络合,在样品分子内产生次级梯度磁场,使各磁核产生不同程度的诱导位移,从而强化化学位移。近几年来,位移试剂在简化波谱,研究立体化学等问题上有很多应用,已有很好的综述,环丙烷系列的化合 Lanthanide shift agents reported earlier. Such reagents in the trivalent metal ions 4f empty orbit, and organic molecules with lone pairs of electronic functional groups such as alcohols, amines, ketones, sulfur ...... and so complex in the sample molecules to produce secondary gradient magnetic field, So that each magnetic core produce varying degrees of induced displacement, thereby enhancing the chemical shift. In recent years, the displacement reagent has many applications in such aspects as simplifying the spectrum and studying stereochemistry. The synthesis of cyclopropane series has been well reviewed