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主张对所有多菌型麻风病人用多药物联合化疗(MDT)有如下几条理由:第一,可以预防原发性和继发性耐药的发生;第二,用作用方式不同的药物联合治疗,可以杀灭不同生长时期的麻风杆菌,因而可以更有效地杀灭细菌;第三,对那些已产生氨苯砜耐药的病人,只有联合化疗才能达到治疗效果。世界卫生组织(WHO)的一个研究组为多菌型麻风病人推荐了一个疗程为2年或更长的多药物治疗方案。许多麻防工作者为了寻找一个杀菌效果最好,复发最少的方案,也对许多方案做了尝试,并提出各种不同疗期的治疗方案。但是只有少数报告对多药物治疗多菌型病人的效果做了长期随访或
Advocates for multidrug-resistant leprosy patients with multi-drug combination chemotherapy (MDT) for several reasons: First, to prevent the occurrence of primary and secondary resistance; second, used as a combination of different ways of drug treatment , Which can kill leprosy at different growth stages and thus kill bacteria more effectively; and thirdly, only those who are resistant to dapsone can achieve their therapeutic effect. A study group from the World Health Organization (WHO) recommended a multi-drug regimen for 2 years or longer for multi-bacteria leprosy patients. In order to find a solution with the best bactericidal effect and minimal relapse, many Mafang practitioners have also tried many programs and proposed various treatment plans for different treatment periods. However, only a few reports have long-term follow-up of the efficacy of multidrug therapy in patients with multi-bacteria