论文部分内容阅读
目的 探讨正电子发射断层扫描 (PET)、脑电图 (EEG)和磁共振成像 (MRI)在儿童难治性癫疒间 病灶定位方面的诊断价值。方法 对 2 2例难治性癫疒间 患儿分别进行 18F FDGPET、EEG和MRI检查 ,并对癫疒间 病灶的检出率及一致性进行比较。结果 PET显像异常率 90 9% (2 0例 ) ,其中低代谢灶 7例 ,高代谢灶 12例 ,低代谢灶和高代谢灶共存 1例。EEG异常率 81 8% (18例 ) ,在病灶诊断上与PET完全一致为 36 .4 % ,部分一致为36 .4 % ,完全不一致为 2 7.2 %。MRI异常率占 4 0 % ,与PET完全一致为 2 5 % ,完全不一致为 75 %。MRI与PET、EEG比较完全一致率 2 0 % ,部分一致率 5 % ,完全不一致率 75 %。结论 PET显像对儿童难治性癫疒间 病灶的探测敏感性高于EEG和MRI ,在病灶诊断上PET与EEG一致性高于PET与MRI。
Objective To investigate the diagnostic value of positron emission tomography (PET), electroencephalography (EEG) and magnetic resonance imaging (MRI) in the localization of intractable epilepsy in children. Methods 18F FDG PET, EEG and MRI were performed in 22 children with intractable epilepsy, and the detection rate and consistency of the lesions between epilepsy were compared. Results The abnormal rate of PET imaging was 90.9% (20 cases), of which 7 cases were low metabolites and 12 cases were hypermetabolites. One case coexisted with low metabolites and high metabolites. The abnormal rate of EEG was 81.8% (18 cases), which was 36.4% identical with PET completely, 36.4% partially consistent and totally 7.2%. MRI abnormalities accounted for 40%, exactly the same with PET 25%, completely inconsistent to 75%. MRI and PET, EEG completely consistent rate of 20%, partial agreement rate of 5%, completely inconsistent rate of 75%. Conclusion PET imaging is more sensitive to detection of intractable epilepsy in children than to EEG and MRI. The consistency of PET and EEG in the diagnosis of PET is higher than PET and MRI.