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目的探讨后肾腺瘤(MA)的临床及病理学特征。方法总结5例MA的临床、影像学、病理学形态特征和免疫组化结果,并行文献复习。结果本组5例后肾腺瘤,男性1例,女性4例。CT平扫表现为界清低密度影;CT血管造影(CTA)提示瘤体呈少血管改变。肉眼观肿瘤境界清楚,呈灰白、灰黄色,质地中等;镜下肿瘤细胞小,均匀一致,核大质少,无异型性及核分裂象,肿瘤细胞呈腺泡状排列,可见乳头状结构,并可见砂砾体钙化。免疫组化示WT-1、CD57和vimentin均(+),S-100、CK7和CKpan部分(+),而CgA、Syn和EMA(-)。术后随访提示预后较好,无复发和转移征象。结论以病理学形态特征结合免疫组化有助于明确后肾腺瘤的诊断。
Objective To investigate the clinical and pathological features of posterior renal adenoma (MA). Methods The clinical, imaging, pathological features and immunohistochemical findings of 5 cases of MA were summarized and reviewed in literature. Results The group of 5 cases of renal adenoma, 1 males and 4 females. CT scan showed clear low-density shadow; CT angiography (CTA) showed that the tumor was less vascular changes. Macroscopic tumor clear boundary, gray, gray, medium texture; microscopic tumor cells are small, uniform, less nuclear mass, no atypia and mitosis, the tumor cells arranged in alveolar shape, showing papillary structures and Visible gravel calcification. Immunohistochemistry showed that both WT-1, CD57 and vimentin (+), S-100, CK7 and CKpan parts (+), while CgA, Syn and EMA (-). Postoperative follow-up prompts good prognosis, no recurrence and metastasis signs. Conclusion The combination of pathological features and immunohistochemistry is helpful for the diagnosis of posterior renal adenoma.