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应用多普勒超声心动图测定31例甲状腺功能减退(甲减)患者的左心室收缩功能和舒张充盈速率,并与17例对照者比较。甲减时,心率减慢、左心房增大、左心室心肌重量增高和短轴缩短率降低。左心室舒张早期充盈速率下降,舒张早期与舒张晚期充盈速率比值减低。后者与病程相关,病程3年以上者,该比值异常的发生率明显增高。10例经6个月甲状腺素治疗后,心率增快,左心房内径和左心室心肌重量减低和短轴缩短率增高,但舒张充盈速率无明显改变。研究提示,甲减患者常有左心室功能障碍,且治疗后舒张功能的恢复较收缩功能为慢。
The left ventricular systolic function and diastolic filling rate in 31 patients with hypothyroidism (hypothyroidism) were measured by Doppler echocardiography and compared with 17 controls. Hypothyroidism, the heart rate slowed, left atrial enlargement, increased left ventricular myocardial mass and short axis shortening rate decreased. Early left ventricular diastolic filling rate decreased, early diastolic and diastolic filling rate decreased. The latter is associated with the course of disease, duration of 3 years or more, the ratio of abnormal incidence was significantly higher. 10 cases after 6 months of thyroxine treatment, the heart rate increased, left atrial diameter and left ventricular myocardial mass loss and short axis shortening rate increased, but no significant change in diastolic filling rate. Research suggests that patients with hypothyroidism often have left ventricular dysfunction, and recovery of diastolic function after treatment than the contraction function is slow.