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雄激素是女性生殖生理过程中非常重要而不可缺少的一种激素。因为它是卵泡合成雌激素的前体。血中雄激素水平高,或是其活性增强,均称为高雄激素血症。此种内分泌紊乱,可引起月经失调,不孕,男性化表现及代谢紊乱。正常月经妇女体内雄激素主要来源于卵巢、肾上腺。此外还有部分是由腺外组织转化而来。卵巢卵巢主要合成睾酮0.1mg/d,雄烯二酮1-2mg/d,脱氢表雄酮<1mg/d。卵巢合成雄激素受LH的调控,LH与泡膜细胞的受体结合,激活酶活性,合成雄激素。
Androgen is a very important and indispensable hormone in female reproductive physiology. Because it is a precursor of follicles that synthesize estrogen. Androgen in the blood is high, or its activity is enhanced, are known as hyperandrogenism. This endocrine disorders, can cause menstrual disorders, infertility, masculine performance and metabolic disorders. Normal menstruation women androgen mainly from the ovary, adrenal. In addition there are some from outside the gland transformation. Ovarian ovarian major synthetic testosterone 0.1mg / d, androstenedione 1-2mg / d, DHEA <1mg / d. Ovarian synthesis androgen by the regulation of LH, LH and foam cell receptor binding, activation of enzyme activity, synthesis androgen.