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对A群流脑多糖体菌苗(下称流脑苗)基础免疫(下称基免)1针增至2针以及2针不同间隔时间的免疫效果作了研究。结果为:基免2针间隔1月组免后1月的近期效果与基免1针组比无差异;基免2针不同间隔时间各组免后1年阳性率在58.12~76.39%的较高水平,基免1针组则降至5.4%的低水平。表明流脑苗基免2针组远期免疫效果优于1针组,而基免2针间隔1月组免后1月、间隔半月组免后半年的阳性率(0.52%和53.71%)均又高于间隔2月组的阳性率(25.44%和30.70%),故认为2针间隔以半月或1月为宜。
The immunogenicity of a group A streptococcal polysaccharide vaccine (hereinafter referred to as ECB) basic immunization (hereinafter referred to as free) from 1 needles to 2 needles and 2 needles at different intervals were studied. The results were as follows: There was no difference in the short-term effect between Jan-Jan and Jan-Jan based on the 2-needle-1-month interval. The positive rate of 1-year post-1-year was 58.12 ~ 76 in different intervals. 39% of the high level, the basic 1-needle group fell to a low level of 5.4%. The results showed that the long-term immunocompetence of meningitis seedling-free 2-needle group was superior to that of the 1-needle group, while the positive rate of 2-month survival rate was 0.52% and 53.5% in the 2-month interval group. 71%) were higher than the interval of February group positive rate (25.44% and 30.70%), so that the 2-pin interval to half or January is appropriate.