患者高某,女,34岁,河南人。1975年3月发现左肺结核后,曾多次住院用异烟肼、对氨柳酸钠、链霉素、异烟腙、卡那霉素、氨硫脲等药物治疗,效果不佳。于1976年12月4日晨改用利福平(波兰出品)600毫克和乙胺丁醇1,000毫克空腹一次口服,当日晚患者感觉全身不适,如感冒样症状,但未作任何处理。第二天晨仍照常服用同样剂量利福平,下午患者开始发冷,发热39℃,咳嗽加剧,打喷嚏,诉全身酸疼难受。为了观察是否 High patient, female, 34 years old, Henan. In 1975 March after the discovery of left pulmonary tuberculosis, has repeatedly hospitalized with isoniazid, sodium salicylate, streptomycin, isoniazid, kanamycin, thiourea and other drug treatment, ineffective. On the morning of December 4, 1976, oral administration of 600 mg of rifampicin (produced in Poland) and 1,000 mg of ethambutol on an empty stomach was administered orally on the night of December 4, 1976. Patients were feeling unwell at night, such as a cold-like symptom but without any treatment. The next morning the same dose of rifampicin was still taken as usual. In the afternoon, patients began to have chills, fever 39 ° C, increased cough, sneezing, and complained of general aches and pains. In order to observe whether