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就在本刊截稿前夕,广州中山大学肿瘤防治申心研制的非典候选疫苗已经出笼,疫苗研究已进入动物实验阶段。中山大学黄文林教授所带领的实验组在非典疫苗的研究上进展迅速,该实验组4月20日开始进行非典 DNA 疫苗和腺病毒携带 SARS郜分 S 基因疫苗的研究。目前,DNA 疫苗研究方面,专家们已将核酸疫苗注射到了大白鼠体内,成功后便可在猴子身上进行动物保护实验,接着就能进行临床实验了。5月26日,记者通过对第二军医大学候选疫苗研制的课题负责人的采访后获悉,“二军医大”候选疫苗已经构建完毕,准备投入动物实验。由于后面的动物试验需要很严格的工作环境(如需在 P3式验室中进行)和3～4个月的观察时间,在动物试验后,核酸疫苗的申报会走“绿色通道”以缩短资料准备的时间,有关专家预计核酸疫苗的最终推出时间在4～5个月之后。疫苗的研制让人们看到最终制服 SARS 的希望。此外,预防、治疗 SARS 新药的研制形势更是令人鼓舞。5月26日,记者获悉,
Just before the essay was published in this issue, the SARS Candidate Vaccine developed by Cancer Center of Sun Yat-sen University in Guangzhou was released and the vaccine research has entered the stage of animal experiments. The experimental group led by Professor Huang Wenlin of Sun Yat-sen University has made rapid progress in SARS vaccine research. The experimental group started the research on SARS-DNA vaccine and adenovirus-carrying SARS-S gene vaccine on April 20. At present, DNA vaccine research, experts have injected nucleic acid vaccine in rats, the success of animal experiments can be carried out in monkeys, and then be able to carry out clinical trials. On May 26, the reporter learned through an interview with the person in charge of the candidate vaccine development project of the Second Military Medical University that the candidate vaccine of the “Second Military Medical University” has been completed and is ready for input into animal experiments. Since subsequent animal tests require very stringent working conditions (if required in P3 laboratories) and observation durations of 3 to 4 months, the declaration of the nucleic acid vaccine will go “green channel” after the animal test Shorten the time to prepare information, the experts predict the final launch of nucleic acid vaccine in 4 to 5 months later. Vaccine development so that people see the hope of finally subduing SARS. In addition, the prevention and treatment of SARS drug development situation is even more encouraging. May 26, the reporter was informed,