r-谷氨酰转肽酶(r-Glutamyl transpeptidase,亦称 r-Clutamyl transferase,简称 r-GT,EC2、3、2、2)是一种广泛分布的质膜结合酶。一般的蛋白水解酶如木瓜蛋白酶等的体外很难水解谷胱甘肽(ESH)中连接 r-谷氨酰基的酰胺键。1930年 Grassman 等发现在组织中很容易分解这种键。1952年 Haines 等从羊肾提取液中发现能分解含 r-谷氨酰的肽类,并将其 r-谷氨酰基转移给其他肽类和 L-氨 Glutamyl transpeptidase (r-Glutamyl transpeptidase, also known as r-Clutamyl transferase, referred to as r-GT, EC2,3,2,2) is a widely distributed membrane-bound enzyme. General proteolytic enzymes such as papain and the like are very difficult to hydrolyze glutathione-linked amide bonds in glutathione (ESH). In 1930 Grassman et al. Found that this bond was easily broken down in tissues. In 1952, Haines et al. Found that peptides containing r-glutamyl can be degraded from sheep kidney extract and their r-glutamyl groups were transferred to other peptides and L-ammonia