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美花风毛菊〔Saussurea pulchella (Fisch.)Fisch.〕的全草在藏医用作催吐、解热、止痛、止血剂,并可治疗慢性风湿性关节炎。此外,在外贝加尔民间尚用全草煎剂治疗腹泻。 (?)于1972年发现美花风毛菊地上部分含有酚类化合物。比较层析证明,在叶和花序中含有黄酮和黄酮醇类化合物。在紫外光下观察色谱图可见到6个含有酚类化合物的斑点。试材(叶和花序)于盛花期采集。风干品碾成粉末(1kg),在80%的甲醇溶液(1:5,5次)中,经水浴加热回流(每份样品40min)。萃取液混合、过滤、在60~70℃下减压浓缩,去除甲醇。为了去掉叶绿素及其它杂质,水剩留物用氯仿提取、浓缩至0.5L。类黄酮物用双向纸色谱法在溶剂系统:正丁醇-冰醋酸-水
The whole plant of Saussurea pulchella (Fisch.) Fisch. is used in Tibetan medicine as an antiemetic, antipyretic, analgesic, haemostatic agent and treats chronic rheumatoid arthritis. In addition, in the Waibaier folk still use whole plant decoction to treat diarrhea. (?) In 1972, it was discovered that the aerial parts of the American flower zephyrrin contained phenolic compounds. Comparative chromatography demonstrated that flavonoids and flavonol compounds were contained in leaves and inflorescences. Observation of the chromatograms under UV light revealed six spots containing phenolic compounds. The test materials (leaves and inflorescences) were collected at flowering stage. The air-dried product was ground into a powder (1 kg) and heated in a water bath (40 minutes per sample) in an 80% methanol solution (1:5, 5 times). The extract was mixed, filtered, and concentrated under reduced pressure at 60 to 70°C to remove methanol. To remove chlorophyll and other impurities, the water remnants were extracted with chloroform and concentrated to 0.5L. Flavonoids with bidirectional paper chromatography in solvent system: n-butanol-glacial acetic acid-water