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目的探讨米非司酮联合依沙丫啶终止中期妊娠的临床效果。方法将我院收治的62例要求终止中期妊娠的妇女,随机分为对照组和观察组,对照组采用依沙丫啶终止妊娠,观察组采用米非司酮联合依沙丫啶终止妊娠。比较两组引产至胎儿娩出时间,总产程,产后出血情况,并发症发生情况等。结果观察组引产时间、总产程显著短于对照组,差异有统计学意义(P<0.05)。观察组产后出血量显著少于对照组,差异有统计学意义(P<0.05)。两组引产成功率差异无统计学意义(P>0.05)。观察组引产后并发症显著低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生情况经统计学分析,差异无统计学意义(P>0.05)。结论采用米非司酮联合依沙丫啶用于终止中期妊娠疗效显著,引产时间及总产程显著缩短,并发症少,不良反应少,值得临床推广应用。
Objective To investigate the clinical effect of mifepristone combined with ethacrynic acid in terminating mid-term pregnancy. Methods Sixty-two women who were asked to terminate mid-term pregnancy in our hospital were randomly divided into control group and observation group. In the control group, they were terminated by esophageal acarbose. The observation group was terminated by mifepristone combined with etanercept. Comparison of two groups of induced labor to the time of delivery of the fetus, total labor, postpartum hemorrhage, complications and so on. Results In the observation group, the induction of labor and the total labor were significantly shorter than those in the control group (P <0.05). Postpartum hemorrhage in the observation group was significantly less than that in the control group, with significant difference (P <0.05). There was no significant difference in the success rate of induction of labor between the two groups (P> 0.05). The postoperative complications in the observation group were significantly lower than those in the control group (P <0.05). Two groups of adverse reactions were statistically analyzed, the difference was not statistically significant (P> 0.05). Conclusion The combination of mifepristone and etanercept is effective in terminating metaphase pregnancy. The induction of labor and the total labor process are significantly shortened with fewer complications and fewer adverse reactions, which is worthy of clinical application.