中药复方研究中的几个关键性问题

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1.整方研究:复方是由单味药组成,但绝不等于单味药的简单罗列,从功效上讲,其不是相加关系,而是相乘。复方由于制剂过程中的热、光、酶和溶媒作用,会形成新的物质,它反映了复方动态过程的复杂性,是拆方研究不容易发现的。此外,量的变化是较常见,实际上。药味不变,仅药量的变化就可能成了功效不同的另一方,现代药理实验也肯定了量效关系的密切性。2.对药研究:药对是中药配伍(还包括七情和合,君臣佐使)的一个重要体现。在复方的现代研究中,药对应作为研究焦点所在。3.特异性生物指标的建立:目前要解决的一个突出问题是建立起与其功效相关的特异性生物指标,在提倡整方研究的基础上,选择了具有特异性的 1. The research of the formula: The compound is composed of single herbs, but it is not equal to the simple list of single herbs. In terms of efficacy, it is not additive but multiplied. Compounds will form new substances due to the heat, light, enzymes, and solvents in the preparation process. It reflects the complexity of the compound dynamic process and is not easy to find in disassembly studies. In addition, the amount of change is more common and actually. The smell of the drug remains unchanged, and only changes in the drug dose may be the other side of the effect. Modern pharmacology experiments also confirm the closeness of the dose-effect relationship. 2. Research on medicines: Drugs are an important embodiment of the compatibility of traditional Chinese medicines (also including Qiqinghehe and Junchenzuo). In the modern research of compound medicine, medicine correspondence is the focus of research. 3. Establishment of specific biological indicators: A prominent problem to be solved at present is the establishment of specific biological indicators related to its efficacy. On the basis of advocating research on the whole, specific and selective
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