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目的:研究新型牵引装置在结直肠侧向发育型肿瘤(laterally spreading tumor,LST)内镜黏膜下剥离术(endoscopic submucosal dissection,ESD)中的有效性。方法:收集2018年8月—2020年4月首都医科大学附属北京朝阳医院内镜中心经ESD治疗的结直肠LST患者资料,根据手术过程中是否使用牵引,分为传统ESD组(不使用牵引)及牵引辅助ESD组(利用3个夹子和1个橡皮圈组成弹性三角形牵引装置进行牵引)。分析两组总切除时间、黏膜下剥离时间、黏膜下剥离速率以及安全性等相关指标。结果:共纳入54例结直肠LST患者,其中29例为传统ESD组,25例为牵引辅助ESD组。两组年龄、性别构成、病变位置比较差异均无统计学意义(n P>0.05)。牵引辅助ESD组的病变面积为13.30(7.55,15.91)cmn 2,较传统ESD组的6.90(5.50,13.50)cmn 2大,差异有统计学意义(n U=503.50,n P=0.014)。传统ESD组与牵引辅助ESD组总切除时间[48.00(35.50,58.00)min比34.00(29.00,35.00)min,n U=109.00,n P<0.001]和黏膜下剥离时间[(39.52±12.37) min比(25.68±7.37)min,n t=4.89,n P<0.001]比较差异有统计学意义。牵引辅助ESD组黏膜下剥离速率快于传统ESD组[0.17(0.13,0.30)cmn 2/min比0.52(0.30,0.62)cmn 2/min,n U=604.00,n P0.05). The lesion area of traction-assisted ESD group was larger than that of the traditional ESD group [13.30 (7.55, 15.91) cmn 2 VS 6.90 (5.50, 13.50) cmn 2, n U=503.50, n P=0.014]. The total procedure time [48.00 (35.50, 58.00) min VS 34.00 (29.00, 35.00) min, n U=109.00, n P<0.001] and submucosal dissection time (39.52±12.37 min VS 25.68±7.37 min,n t=4.89, n P<0.001) were significantly different between the two groups. In terms of submucosal dissection speed, the assisted-traction ESD group was significantly faster than that of the traditional ESD group [0.17 (0.13, 0.30) cmn 2/min VS 0.52 (0.30, 0.62) cmn 2/min, n U=604.00, n P<0.001]. There were 2 (6.9%) cases of perforation in the traditional ESD group, and no perforation occurred in traction-assisted ESD, but the result was not statistically significant (n P=0.493).n Conclusion:Compared with traditional ESD, traction-assisted ESD with clip and rubber band is safer and more effective in the treatment of colorectal LST.