论文部分内容阅读
目的比较门冬胰岛素30和预混人胰岛素30R对2型糖尿病的疗效。方法 40例2型糖尿病患者,随机分为诺和锐30组和诺和灵30R组,分别采用每日早晚餐前注射诺和锐30和诺和灵30R,进行为期4周的观察。比较4周后两组患者空腹血糖、餐后2h血糖、低血糖发生频率和12周后的糖化血红蛋白。结果两组治疗后空腹血糖、餐后2h血糖、糖化血红蛋白均显著下降(P<0.01),仅1例严重低血糖发生。两组间差异无统计学意义(P>0.05)。结论对于2型糖尿病患者,每日两次注射诺和锐30或诺和灵30R均能安全、有效地降低血糖。
Objective To compare the efficacy of insulin aspart 30 and pre-mixed insulin 30R on type 2 diabetes mellitus. Methods Forty patients with type 2 diabetes mellitus were randomly divided into Novolin 30 and Novolin 30R groups. The rats were anesthetized with Novolin 30 and Novolin 30R respectively in the morning and evening for 4 weeks. The fasting blood glucose, postprandial blood glucose 2h, hypoglycemic frequency and glycated hemoglobin after 12 weeks were compared between the two groups after 4 weeks. Results After treatment, fasting blood glucose, postprandial blood glucose 2h, HbA1c decreased significantly (P <0.01), and only 1 patient had severe hypoglycemia. There was no significant difference between the two groups (P> 0.05). Conclusion In patients with type 2 diabetes, twice daily injection of Novo-Rui 30 or Novolin 30R can safely and effectively reduce blood sugar.