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本文观察了去除卵巢（ＯＶＸ）大鼠在水浸拘束条件下，心肌和主动脉血栓素及前列环素（测其代谢产物ＴＸＢ＿２和６－ｋｅｔｏＰＧＦ＿（１ａ））含量的变化，并观察补充雌激素后的影响。结果：在实施应激后，ＯＶＸ鼠血管ＴＸＢ＿２和６－ｋｅｔｏＰＧＦ＿（１ａ）比值（Ｔ／Ｋ）明显高于假手术应激组（Ｐ＜０．０１），补充雌激素后恢复正常（Ｐ＜０．０５）。提示：雌激素对维持正常心血管舒缩功能，提高机体对外界刺激的适应性方面具有重要作用。
In this study, the changes of thromboxane and prostacyclin (measured TXB_2 and 6-ketoPGF_ (1a)) levels in myocardium and aorta were observed in ovariectomized (OVX) -contained rats and the effects of estrogen replacement After the impact. Results: After stress, the ratio of TXB_2 to 6-ketoPGF_ (1a) in OVX mice was significantly higher than that in sham operation group (P <0.01), and returned to normal after estrogen replacement (P < 0.05). Tip: Estrogen plays an important role in maintaining normal cardiovascular vasomotion and enhancing the body’s adaptability to external stimuli.