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目的:探析应用三联法治疗消化性溃疡的效果。方法:选取该院2013年1月至2015年10月收治的86例消化性溃疡患者,随机将其分为治疗组(46例)和对照组(40例),均采取药物三联治疗,对照组给予雷尼替丁、阿莫西林、甲硝唑治疗,治疗组给予奥美拉唑、阿莫西林、克拉霉素治疗,分析治疗效果。结果:治疗组总有效率86.96%明显优于对照组75.0%;治疗组HP根除率84.78%明显优于对照组52.5%比较差异有统计学意义(P<0.05)。治疗组不良反应发生率6.52%明显低于对照组15.0%,比较差异有统计学意义(P<0.05)。结论:消化性溃疡给予奥美拉唑、阿莫西林、克拉霉素治疗,疗效理想,根除HP概率高,不良反应少,值得应用。
Objective: To investigate the effect of triple therapy on peptic ulcer. Methods: A total of 86 patients with peptic ulcer admitted from January 2013 to October 2015 in our hospital were randomly divided into treatment group (46 cases) and control group (40 cases). All patients were treated with triple therapy and control group Give ranitidine, amoxicillin, metronidazole treatment, the treatment group was given omeprazole, amoxicillin, clarithromycin treatment, analysis of treatment. Results: The total effective rate of the treatment group was 86.96%, which was significantly better than that of the control group (75.0%). The HP eradication rate of the treatment group was significantly higher than that of the control group (84.78% vs 52.5%, P <0.05). The incidence of adverse reactions in the treatment group was significantly lower than that in the control group (6.52% vs 15.0%, P <0.05). Conclusion: Peptic ulcer given omeprazole, amoxicillin, clarithromycin treatment, ideal effect, high probability of eradication HP, adverse reactions, it is worth to apply.