报道1例中年男性患者临床为肾病综合征伴血压升高,无听力及视力的下降,无肾脏病家族史;肾活检光镜及常规免疫荧光符合肾小球膜性病变,但肾间质见簇状分布的泡沫细胞,进一步行肾组织IV型胶原染色及电镜检查,最终明确合并Alport综合征。 Reported a case of middle-aged men with clinical nephrotic syndrome with elevated blood pressure, no hearing loss and decreased visual acuity, no family history of renal disease; renal biopsy light microscopy and routine immunofluorescence in line with the mesangial lesions, but the renal interstitium See clusters of foam cells, further line renal collagen type IV staining and electron microscopy, the final clear merge Alport syndrome.