目的了解宜兴市2005-2012年病毒性肝炎的流行病学特征,为制定病毒性肝炎的防治策略提供科学依据。方法采用描述流行病学方法描述病毒性肝炎疫情的流行特征。结果 2005-2012年宜兴市病毒性肝炎呈现下降趋势,年平均发病率为41.32/10万,存在季节聚集性;以乙肝最多,占61.38%;甲肝、未分型肝炎发病率呈逐年下降趋势;丙肝呈上升趋势,戊肝散发;发病年龄集中在20~59岁年龄组,男女性别比为2.28∶1;农民与工人发病最多。结论宜兴市病毒性肝炎防治应以控制血源性传播肝炎为主,重点加强对乙肝的预防控制,加大重点人群的宣教及疫苗接种工作。 Objective To understand the epidemiological characteristics of viral hepatitis in Yixing City from 2005 to 2012 and to provide a scientific basis for the prevention and treatment of viral hepatitis. Methods Epidemiological methods were used to describe the epidemiological characteristics of the viral hepatitis outbreak. Results The incidence of viral hepatitis in Yixing City showed a decreasing trend from 2005 to 2012 with an average annual incidence of 41.32 / 100 000 with seasonal aggregation; the highest was hepatitis B (61.38%); the incidence of hepatitis A and non-segmented hepatitis was declining year by year; Hepatitis C showed an upward trend and the hepatitis E was exuded. The age of onset was concentrated in the age group of 20-59 years with a sex ratio of 2.28:1. Peasants and workers had the most morbidity. Conclusion The prevention and treatment of viral hepatitis in Yixing should be based on the control of blood-borne hepatitis. The prevention and control of hepatitis B should be emphasized and the mission and vaccination of key populations should be strengthened.