肝静脉闭塞病(VOD)是造血干细胞移植后一个严重的并发症,其发生率在不同的报道有差别,在5%～50%之间。目前随着移植前预处理方案的不断改进及抗感染等支持治疗措施的进一步强化;现认为VOD的发生已成为造血干细胞移植后的重要并发症和近期死亡的原因之一;已引起临床的高度重视。我们在对7例患者造血干细胞移植中,应用凯时(前列地尔脂微球载体制剂)预防VOD,取得了良好效果;现结合文献报告如下。 Hepatic veno-occlusive disease (VOD) is a serious complication after hematopoietic stem cell transplantation, and its incidence varies from 5% to 50% in different reports. At present, with the continuous improvement of pre-transplant programs and support measures such as anti-infectives, it is thought that the occurrence of VOD has become an important complication and a recent cause of death after hematopoietic stem cell transplantation; the clinical highness Pay attention. We have 7 cases of patients with hematopoietic stem cell transplantation, the application of Kay hours (Vital Lipid propolis lipid microsphere preparation) to prevent VOD, and achieved good results; are combined with the literature as follows.