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了解慢性肾功能衰竭（CRF）患者尿表皮生长因子含量的变化及意义。方法：用放射免疫法。结果：CRF患者尿表皮生长因子含量显著低于正常对照组，与年龄、血肌酐、尿素氮、血β2-微球蛋白呈显著负相关，但与病程、尿β2-微球蛋白无显著相关性。结论：尿表皮生长因子可作为反映肾功能衰竭患者病情严重性的一个指标。
To investigate the changes and significance of urinary epidermal growth factor in patients with chronic renal failure (CRF). Methods: By radioimmunoassay. Results: The urinary epidermal growth factor levels in CRF patients were significantly lower than those in normal controls, but negatively correlated with age, serum creatinine, blood urea nitrogen and blood β2-microglobulin, but not with disease duration and urine β2-microglobulin . Conclusion: Urine epidermal growth factor can be used as an indicator of the severity of renal failure patients.