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目的 :探讨肺栓塞溶栓与抗凝治疗的疗效及出血风险的对比。方法 :收集2011年5月~2015年2月我院的肺栓塞患者,随机分为2组:82例观察组(给予溶栓治疗)和54例对照组(给予抗凝治疗)。结果 :(1)观察组和对照组肺栓塞治疗疗效结果比较有差异(P<0.05)。(2)观察组和对照组肺栓塞复发及严重出血分别为(0例、4例)、(3例、1例),结果:比较无差异(P>0.05)。结论:本次研究认为对无溶栓禁忌症者,应采取溶栓治疗,以降低复发风险和病死率。
Objective: To investigate the curative effect of pulmonary thrombolysis and anticoagulation therapy and the risk of bleeding. Methods: The patients with pulmonary embolism in our hospital from May 2011 to February 2015 were randomly divided into two groups: 82 cases in observation group (given thrombolytic therapy) and 54 cases in control group (given anticoagulant therapy). Results: (1) There were significant differences between the observation group and the control group in the treatment effect of pulmonary embolism (P <0.05). (2) The relapse and severe hemorrhage of pulmonary embolism in observation group and control group were (0 cases, 4 cases), (3 cases, 1 case). There was no difference between the two groups (P> 0.05). Conclusion: This study suggests that thrombolytic therapy should be taken for contraindications without thrombolysis in order to reduce the risk of recurrence and mortality.