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胸腹水涂片中细胞学诊断较困难的问题是增生间皮细胞与不典型的恶性肿瘤细胞的鉴别,因此寻找一种较客观的形态学诊断指标是十分重要的。晚近,国外报道用银染新技术显示石蜡组织切片上核仁组成区嗜银蛋白(Ag-staining nuclcolar organizerRegion,AgNOR)鉴别良恶性肿瘤获得成功,我们应用AgNOR染色技术对胸腹水涂片中的反应性增生间皮细胞及癌细胞进行形态定量检测,探讨鉴别二者的可能性。
Ascites and pleural effusion cytology more difficult to diagnose the problem is the proliferation of mesothelioma and atypical malignant cells to identify, so to find a more objective morphological diagnostic indicators is very important. Recently, foreign reports using silver staining new technology shows paraffin section of the paraffin section of the nucleolar organizer region of Agronomic protein (AgNOR) differential diagnosis of benign and malignant tumors, we use AgNOR staining of pleural effusion smear response Proliferation of mesothelial cells and cancer cells morphological quantitative detection, to explore the possibility of identifying the two.