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目的探讨Klippel-Trenaunay-Weber综合征(KTWS)血管内介入治疗的可行性。方法对14例KTWS患者行患肢动脉造影,分别以平阳霉素+超液化碘油、聚乙烯醇颗粒(PVA)、氰丙烯酸盐黏合剂(NBCA)、钢圈进行血管内介入治疗。结果术后所有患者患肢血管瘤(痣)病变和浅静脉曲张明显改善或消失。术后并发症主要为栓塞区域疼痛(9例)、水肿(14例),3例患者出现整条患肢水肿,10例在术后7-9 d自然消退。术后随访1个月,栓塞区域血管瘤(痣)病变有进一步改善,患肢大腿中部周径和膝下10 cm周径分别缩小(2．1±0.3)cm和(2．0±0．2)cm,3例患肢淋巴水肿和3例股浅静脉返流均有所改善。结论采用血管内介入治疗KTWS效果是显著的。
Objective To investigate the feasibility of endovascular interventional therapy with Klippel-Trenaunay-Weber syndrome (KTWS). Methods 14 cases of KTWS patients underwent arterial angiography, respectively, Pingyangmycin + hyperlipemia lipiodol, polyvinyl alcohol particles (PVA), cyanoacrylate adhesive (NBCA), steel endovascular interventional treatment. Results All patients had hemangiomas (nevus) and varicose veins significantly improved or disappeared after operation. Postoperative complications were mainly embolization (9 cases) and edema (14 cases). The entire limb edema occurred in 3 cases and spontaneous subsidence in 7 cases (9 days) after operation. One month after surgery, the lesions in the embolic area were further improved. The diameter of the middle thigh and the circumference of 10 cm of the knee were reduced (2.1 ± 0.3) cm and (2.0 ± 0.2) mm respectively ) cm, 3 cases of limb lymphedema and 3 cases of superficial femoral vein reflux were improved. Conclusion The results of endovascular treatment of KTWS are significant.