粘膜皮肤淋巴结综合征近来已被称之为一独立的临床疾病,是川琦氏在1967年首先报道的,迄今在日本资料中已经报道近7000例。朝鲜曾经报道过8例,夏威夷12例,希腊8例。在美国大陆尚未见有本综合征的报告,但新近的一次复习提示此病确实在美国存在。本文报告3例,均发生于田纳西州,1例在1974年11月发病,2例分别于1975年5及6月发病。3例均有以下的粘膜皮肤淋巴结综合征的临床特征:发烧、颈淋巴腺炎、球结膜充血、多种形态的皮疹、掌跖红斑、手足硬肿、口腔粘膜发红、口唇干裂、杨梅状舌、腹泻及指(趾)脱屑等,2例有关节痛。实验室检查示:白细胞增多,轻度贫血、无菌脓 Mucosal cutaneous lymph node syndrome has recently been described as an independent clinical disease, which was first reported by Chuanqi in 1967, to date, nearly 7000 cases have been reported in Japanese data. North Korea has reported 8 cases, Hawaii 12 cases, Greece 8 cases. No such syndrome has been reported in the continental United States, but a recent review suggested that the disease does exist in the United States. This article reports 3 cases, all occurred in Tennessee, 1 case of onset in November 1974, 2 cases were onset in May and June 1975. All of the 3 cases had the following clinical features of mucocutaneous lymph node syndrome: fever, cervical lymphadenitis, conjunctival hyperemia, rash of various forms, palmoplantar erythema, schizophrenia, oral mucosa redness, chapped lips, bayberry Tongue, diarrhea and finger (toe) scaling, 2 cases of joint pain. Laboratory tests showed: leukocytosis, mild anemia, sterile pus