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载脂蛋白A-Ⅰ是血浆高密度脂蛋白的主要蛋白成份,在生理浓度下能抑制单纯疱疹Ⅰ型病毒引起的细胞融合。作者选用了三种来源的血浆载脂蛋白A-Ⅰ及其中一种的裂解片段,通过三种不同的实验研究了其抗病毒作用,并认为此作用与A-Ⅰ的氨基酸组成及其相应的空间结构有密切关系。
Apolipoprotein A-I is a major protein component of plasma HDL and inhibits herpes simplex virus-induced cell fusion at physiological concentrations. The authors selected three sources of plasma apolipoprotein A-Ⅰ and one of the cleavage fragments by three different experiments to study its antiviral effect, and that this effect with A-Ⅰ amino acid composition and its corresponding The spatial structure is closely related.