血管紧张素Ｉ（ＡｎｇＩ）受体虽然缺乏内源性蛋白酪氨酸激酶活性，但它却细胞内信号转导的磷脂酶Ｃ磷酸肌醇途径、酶蛋白受体Ｒａｓ途径和ＪＡＫ／ＳＴＡＴ途径中多种信号分子，及其受体本身和粘着斑激酶等分子的酪氨酸磷酸化密切相关。蛋白酪氨酸磷酸化是细胞转导生长与分化信号的重要机制。本文叙述血管平滑肌细胞和心脏细胞在ＡｎｇＩ受体各信号转导途径中的蛋白酪氨酸磷酸化现象。 Although angiotensin I (AngI) receptor lacks endogenous protein tyrosine kinase activity, it has intracellular signal transduction phospholipase C phosphoinositide pathway, enzyme protein receptor Ras pathway and JAK / STAT Pathways of a variety of signaling molecules, and its receptor itself and focal adhesion kinase and other molecules tyrosine phosphorylation is closely related. Protein tyrosine phosphorylation is an important mechanism of signal transduction and differentiation of cells. This article describes the protein tyrosine phosphorylation of vascular smooth muscle cells and cardiac cells in the various signaling pathways of AngI receptors.