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目的探讨慢性萎缩性胃炎的临床特点和规范治疗的方法,并对治疗效果进行评价。方法选取2015年2月-2016年2月医院收治的120例慢性萎缩性胃炎患者为研究对象,随机分为观察组和对照组,每组各60例。观察组采用奥美拉唑合并替普瑞酮治疗,对照组采用奥美拉唑治疗,比较2组临床疗效。结果观察组的总有效率为90.0%,高于对照组的55.0%,差异具有统计学意义(P<0.05)。结论对于慢性萎缩性胃炎的患者采用奥美拉唑联合替普瑞酮进行治疗,患者治疗效果较好,不良反应发生率下降,值得临床推广应用。
Objective To investigate the clinical features of chronic atrophic gastritis and standardize the treatment methods, and to evaluate the therapeutic effect. Methods A total of 120 patients with chronic atrophic gastritis admitted in our hospital from February 2015 to February 2016 were selected as study subjects and randomly divided into observation group and control group with 60 cases in each group. The observation group was treated with omeprazole and teprenone, while the control group was treated with omeprazole. The clinical efficacy was compared between the two groups. Results The total effective rate in the observation group was 90.0%, which was higher than that in the control group (55.0%), the difference was statistically significant (P <0.05). Conclusion Omeprazole combined with teprenone was used in patients with chronic atrophic gastritis. The treatment effect was good and the incidence of adverse reactions decreased, which deserved clinical application.