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1979年我国首次报告亚硒酸钠、维生素E(VE)治疗大骨节病取得显著效果。同年7月至1981年3月河南省卫生防疫站、中国科学院地理研究所和灵宝县防疫站联合在河南又重复了该项实验并作了动态观察。同时对水、粮、发中硒及血中谷胱甘肽过氧化物酶(GSH-px)、VE含量作了测定。认为骨质的修复是补充硒及VE的结果,并表明大骨节病区为低硒地区。
1979 China’s first report of sodium selenite, vitamin E (VE) treatment of Kashin-Beck disease achieved significant results. In July the same year in July 1981 to Henan Province Health and Epidemic Prevention Station, Institute of Geography, Chinese Academy of Sciences and Lingbao County epidemic prevention station in Henan repeated the experiment and made a dynamic observation. In the meantime, the content of selenium and glutathione peroxidase (GSH-px) and VE in blood, food and hair were measured. That bone repair is the result of selenium and VE supplementation, and shows that Kashin-Beck area for the low selenium areas.