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简述从四氢吡喃丙炔醇（３）和１－溴－４－氯丁烷（４）开始经６步反应制备７－氰基－１－二甲步丁硅氧基－２－，３－反－环氢庚烷（５），此化合物是合成（＋）－布雷菲德菌素Ａ中间体的原料。
A brief description of the preparation of 7-cyano-1-dimethylbutylsiloxy-2- from tetrahydropyranyl propargyl alcohol (3) and 1-bromo-4-chlorobutane (4) 3-trans-cycloheptane (5), which is a starting material for the synthesis of (+) - brefeldin A intermediate.