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16例甲状旁腺功能减退患者,包括6例假性甲状旁腺功能减退症(PHP),6例特发性甲状旁腺功能减退症(IHP)和4例手术性甲状旁腺功能减退症(SHP)接受神经学检查,脑的电子计算机断层扫描摄影和颅骨X线摄片,在上述前两组病例作中型甲状旁腺激素静脉注入后,测量血浆中Se—甲状旁腺激素和单磷酸3’、5’环腺酸苷。 治疗前所有病例都遭受过癫痫的发作及由于低钙血症所致的手足搐搦症状,1例PHP患者显示小午蹈病发作,脑电图呈弥散性异常,Chvestek征和Trousseau征惯常存在,CT扫描显示对称性,实质性脑钙化斑在PHP患者中占6例,在IHP患者中占4例,然而在X线颅片上的钙化斑10例中只
Sixteen patients with hypoparathyroidism, including 6 cases of pseudo-hypoparathyroidism (PHP), 6 cases of idiopathic hypoparathyroidism (IHP) and 4 cases of surgical hypoparathyroidism (SHP ) Underwent neurological examinations, computerized tomography of the brain and skull radiographs. After the above two groups of patients were injected intravenously with a medium parathyroid hormone, plasma Se-parathyroid hormone and 3 ’ , 5 ’cyclic adenosine. 1 case of PHP patients showed episodes of chorioretinopathy, EEG diffuse abnormalities, Chvestek sign and Trousseau sign used to be often present, and all the cases were treated with epilepsy and symptoms of tetany due to hypocalcemia. CT scans showed symmetry. Substantial brain calcification plaques accounted for 6 of PHP patients and 4 of IHP patients, whereas in 10 cases of calcified plaque on the X-ray cranium