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为了探讨胆红素水平对早产儿智力远期影响,对283例黄疸早产儿在5-8岁时进行智商测定。结果显示:121例(42.76%)有程度不同的IQ低下(IQ≤70),胆红素峰值越高,IQ异常率越高(除342mmol/L~组与204mmol/L~及275mmol/L~组比较无显著性差异外,其它各组比较均有显著性差异)。其中IQ小于55的早产儿29例(10.25%),合并有高危因素明显高于IQ小于70组(除342mmol/L~组外,其它各组均有显著性差异)。提示:早产儿远期智力低下与胆红素峰值有关,同时受体重小于1500g、新生儿期感染、缺氧、酸中毒、低蛋白血症等高危因素影响。
In order to explore the long-term effects of bilirubin on the intelligence of premature children, 283 preterm infants with jaundice were measured at 5-8 years old. The results showed that 121 cases (42.76%) had different degree of IQ (IQ≤70), the higher the bilirubin peak, the higher the rate of IQ abnormality (except 342mmol / L ~ group and 204mmol / L ~ L ~ group was no significant difference, the other groups were significantly different). Among them, 29 (10.25%) preterm infants with IQ less than 55 had significantly higher risk factors than those with IQ less than 70 (all other groups except 342mmol / L ~). Tip: The long-term mental retardation in preterm infants and bilirubin peak related to the same time by the body weight less than 1500g, neonatal infection, hypoxia, acidosis, hypoproteinemia and other risk factors.