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良性前列腺增生在中老年男性中属常见病、多发病,可引起排尿困难、尿潴留,甚至肾衰竭。代谢综合征亦多发于中老年,近年的研究表明,代谢综合征可能与前列腺增生的发生密切相关。相对于健康人群而言,代谢综合征患者更容易出现前列腺增生。代谢综合征可通过提高交感神经活性、刺激胰岛素样生长因子分泌、高胰岛素血症、影响激素水平、氧化应激以及缺血缺氧等机制参与良性前列腺增生的发生和发展。
Benign prostatic hyperplasia in the middle-aged men is a common disease, frequently-occurring disease, can cause dysuria, urinary retention, and even renal failure. Metabolic syndrome is also common in middle-aged and elderly, recent studies have shown that metabolic syndrome may be closely related to the occurrence of benign prostatic hyperplasia. Relative to healthy people, patients with metabolic syndrome are more prone to prostate hyperplasia. Metabolic syndrome can participate in the occurrence and development of benign prostatic hyperplasia by enhancing sympathetic nerve activity, stimulating insulin-like growth factor secretion, hyperinsulinemia, influencing hormone levels, oxidative stress and hypoxia / hypoxia.