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国内较为系统研究和应用神经行为方法始于 80年代初。 1986年引入世界卫生组织神经行为核心测试组合 ( NCTB) ,使之中文化 ,制成中文版本。同时对影响测试结果的主要混杂因素 ,如受试者年龄、性别、文化水平进行了深入研究 ,并建立了按年龄、性别、文化水平分组的 5 5 4名无环境有害因素接触史健康者 NCTB的参比值。此外 ,还发展出用因子分析和聚类分析法来研究NCTB。在此期间 ,于 1988年国内首次研制出中文化神经行为评价系统 ( NES- C1)用于检测工人神经行为功能。在此基础上 ,于 1992年和 1998年分别发展出性能更为良好的第二代 ( NES- C2 )和第三代 ( NES- C3)中文化神经行为测试评价系统。在现场调查中 ,用 NCTB和 NES对受检者测试结果表明 ,两者的效度、信度及灵敏度俱佳 ,是检测环境有害因素对中枢神经系统早期不良影响的一个极为有用的工具。在此还介绍了环境有害因素如铅、锰、铝及二甲苯等致神经行为改变的可能生物学基础
More systematic research and application of neural behavior in China began in the early 1980s. In 1986, the World Health Organization core behavioral testing (NCTB) was introduced into Chinese and made into a Chinese version. At the same time, the main confounding factors that affect the test results, such as subjects age, gender and cultural level were studied in depth and 5 54 non-environmental harmful factors were established by age, sex and cultural level to contact NCTB Of the reference value. In addition, factor analysis and cluster analysis have also been developed to study NCTB. In the meantime, in 1988, the first Chinese-made neural behavioral assessment system (NES-C1) was developed in China to test the neurobehavioral function of workers. On this basis, the second generation (NES-C2) and third generation (NES-C3) cultural neurobehavioral evaluation systems were developed in 1992 and 1998, respectively. In the field investigation, the test results of the subjects with NCTB and NES showed that the validity, reliability and sensitivity of the two were excellent, which was an extremely useful tool for detecting the early adverse effects of environmental harmful factors on the central nervous system. Here is also a description of the possible biological basis of environmentally responsible changes in the behavior of the environment such as lead, manganese, aluminum and xylene