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目的了解新疆克孜勒苏柯尔克孜自治州(简称克州)细粒棘球蚴病的流行情况,为该地区棘球蚴病的防治提供依据。方法2011-2012年,在克州的乌恰县、阿图什市、阿克陶县和阿合奇县等4县(市)共抽取农业区和牧业区19个乡(镇)的62个行政村作为调查点。对各调查点的所有常驻居民采用常规腹部B超检查棘球蚴病患病情况,用ELISA检测6~12岁儿童血清抗棘球蚴抗体水平。采集家犬新鲜粪便,ELISA检测犬粪样中棘球绦虫抗原。调查4县(市)的屠宰厂,用触摸和肉眼观察屠宰家畜的棘球蚴包囊情况。结果克州4县(市)共B超检查12 000人,患病者60例,均为细粒棘球蚴病,患病检出率为0.5%(60/12 000),其中乌恰县最高,为1.1%(35/3 200),与阿图什市(0.5%,13/2 400)、阿克陶县(0.2%,8/3 200)和阿合奇县(0.1%,4/3 200)的比较,差异有统计学意义(χ~2=4.92~24.79,P<0.05)。患病检出率以≥71岁年龄组最高,为1.2%(4/323);0~10岁年龄组次之,为0.9%(3/350),各年龄组间的比较差异无统计学意义(χ~2=0.39~3.31,P>0.05)。儿童血清学调查结果显示,抗体阳性率为3.1%(230/7 338),其中阿图什市最高,为4.9%(89/1 828),与阿克陶县(2.9%,56/1 927)和乌恰县(0.7%,11/1 639)的比较差异有统计学意义(χ~2=9.71,54.34,P<0.05)。犬粪抗原阳性率为3.3%(74/2 219)。屠宰家畜调查结果显示,患病检出率为7.7%(291/3 769),其中以羊占最多,为97.3%(283/291)。结论克州细粒棘球蚴病人群患病检出率以乌恰县最高(1.1%),儿童血清学抗体阳性率以阿图什市最高(4.9%),并存在患病家畜和感染犬。
Objective To understand the epidemic situation of Echinococcus granulosus in Xinjiang Autonomous Prefecture of Kizilsu (Autonomous Prefecture of Kizils), and to provide basis for the prevention and control of echinococcosis in this area. Methods From 2011 to 2012, a total of 19 townships (towns) in agricultural and pastoral areas were sampled from 4 counties (cities) in Wuqia County, Atushi City, Akto County, and Akchi County in Ke Prefecture An administrative village as a survey point. The prevalence of echinococcosis was examined by routine abdominal B-ultrasound in all resident residents at each survey site. Serum anti-hydatid antibody levels were measured by ELISA in children aged 6 to 12 years. Fresh domestic dog feces was collected and ELISA was used to detect Echinococcus antigen in dogs and cats. Investigate 4 counties (cities) slaughter plant, with the touch and naked eye slaughtering livestock echinococcosis cysts. Results A total of 12 B-ultrasound and 60 patients were diagnosed in 4 counties (counties) of Kezhou County, all of which were echinococcus granulosus, the prevalence rate was 0.5% (60/12 000), among which, Wuqia County The highest rate was 1.1% (35/3 200) in the cities of Atushi (0.5%, 13/2 400), Akto County (0.2%, 8/3 200) and Ajiki (0.1%, 4 / 3 200), the difference was statistically significant (χ ~ 2 = 4.92 ~ 24.79, P <0.05). The prevalence of the disease was highest in the group of ≥71 years old (1.2%, 4/323), followed by that in the group of 0-10 years old (0.9%, 3/350), with no significant difference among all age groups Significance (χ ~ 2 = 0.39 ~ 3.31, P> 0.05). The results of the serological survey in children showed that the positive rate of antibody was 3.1% (230/7 338), of which the highest in Atushi City was 4.9% (89/1 828), which was similar to that in Akto County (2.9%, 56/1 927 ) And Wuqia County (0.7%, 11/1639). There was significant difference between them (χ ~ 2 = 9.71,54.34, P <0.05). The positive rate of canine antigen was 3.3% (74/2 219). Slaughter livestock survey results showed that the prevalence was 7.7% (291/3 769), of which sheep accounted for the largest 97.3% (283/291). Conclusion The prevalence rate of echinococcus granulosus in Zhuzhou is the highest (1.1%) in Wuqia County and the highest in children (4.9%) in Atushi, with the presence of sick and infected dogs .