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目的探讨乳腺叶状肿瘤复发、转移因素,为术式的选择提供帮助。方法回顾性分析解放军总医院1998年1月-2009年10月间经手术并经病理诊断的66例乳腺叶状肿瘤的临床病理资料,分析其诊断治疗情况。结果66例中,恶性11例,交界性3例,良性52例。初次手术即在我院者57例,随访39例,6例局部复发(15.4%),其中良性2例,交界性1例,恶性3例。复发后来我院诊治9例,随诊7例,再次复发4例(57.1%)。因肺转移死亡3例,均为多次局部复发的恶性叶状肿瘤患者。结论再次局部扩大切除术后仍复发的良性病例,及初次复发的恶性病例,应尽早行乳腺切除术。
Objective To investigate the recurrence and metastasis of breast phyllodes tumor and provide help for the selection of surgical procedures. Methods The clinical and pathological data of 66 cases of breast phyllodes tumor which were surgically and routinely diagnosed by PLA General Hospital from January 1998 to October 2009 were analyzed retrospectively to analyze their diagnosis and treatment. Results Among the 66 cases, 11 were malignant, 3 were borderline and 52 were benign. The first operation was in our hospital 57 cases, followed up 39 cases, 6 cases of local recurrence (15.4%), including 2 cases of benign, borderline 1 cases, 3 cases of malignancy. After the recurrence, 9 cases were diagnosed and treated in our hospital, 7 cases were followed up and 4 cases (57.1%) relapsed again. Three patients died of lung metastases, all of whom were patients with malignant phyllodes tumor with multiple local recurrences. Conclusions Again local enlargement of the recurrence after resection of the benign cases, and the initial recurrence of malignant cases, mastectomy should be performed as soon as possible.