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2010年5月3日出版的《临床研究杂志》(J Clin Invest)刊载了一篇关于心力衰竭的研究论文,题为“心肌胰岛素信号通路的过度激活加重了压力负荷导致的心脏功能障碍”。因该义与我们目前从事的研究密切相关,我们课题组对该论文进行了深入讨论,对作者关于胰岛素及其信号通路与心肌肥厚的关系提出了质疑,所撰写的两篇Letter干2010年年5月4日和5月5日相继在《J Clin Invest》官方网站上刊登。随后该文作者之一美国犹他大学Abel教授专程来访我校,就相关问题与我们进行了面对面的探讨,并促成了双方合作。
J Clin Invest, May 3, 2010, published a research paper on heart failure titled “Excessive activation of the myocardial insulin signaling pathway aggravates cardiac dysfunction due to stress load. ”. Because of the close relationship between the meaning and the research we are currently engaged in, our research group conducted an in-depth discussion of the paper and questioned the author about the relationship between insulin and its signaling pathway and cardiac hypertrophy. May 4 and May 5 in the “J Clin Invest” official website. Then, one of the authors of this paper, Professor Abel from Utah University, made a special trip to visit our school to conduct face-to-face discussions on the relevant issues and to promote cooperation between the two parties.