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目的探讨益母草注射液联合缩宫素预防剖宫产产后出血的效果及安全性。方法选取2012年1月—2014年11月于永修县三溪桥镇卫生院行剖宫产的产妇210例,根据治疗方案不同分为研究组与对照组,各105例。对照组产妇予以缩宫素治疗,研究组产妇在对照组基础上加用益母草注射液治疗。观察两组产妇术中出血量、术后4、24h出血量、产前及产后24h血红蛋白水平、红细胞计数及不良反应发生情况。结果研究组产妇术中出血量、术后4、24h出血量少于对照组,差异有统计学意义(P<0.05);产前两组产妇血红蛋白水平、红细胞计数比较,差异无统计学意义(P>0.05),产后24h研究组产妇血红蛋白水平、红细胞计数高于对照组,差异有统计学意义(P<0.05);两组产妇不良反应发生率比较,差异无统计学意义(P>0.05)。结论益母草注射液联合缩宫素预防剖宫产产后出血的效果显著,对产妇血红蛋白水平及红细胞计数影响小,且不良反应少,安全性高。
Objective To investigate the effect and safety of motherwort injection combined with oxytocin in preventing bleeding after cesarean section. Methods A total of 210 maternal women who underwent caesarean section from January 2012 to November 2014 in Sanxiqiao Town Hospital of Yongxiu County were divided into study group and control group with 105 cases in each group. The control group maternal to oxytocin treatment, the study group maternal in the control group based on the use of motherwort injection therapy. The bleeding volume, the amount of bleeding at 4 and 24 hours after operation, the hemoglobin level at prenatal and postnatal period, erythrocyte count and adverse reactions were observed. Results The amount of bleeding in the study group was less than that in the control group at 4 and 24 hours after operation, and the difference was statistically significant (P <0.05). There was no significant difference in hemoglobin level and erythrocyte count between the two groups P> 0.05). The hemoglobin level and erythrocyte count of the study group were significantly higher than those of the control group after 24 hours (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05) . Conclusion Motherwort injection combined with oxytocin to prevent bleeding after cesarean section has a significant effect on maternal hemoglobin levels and erythrocyte count, and less adverse reactions, high safety.