论文部分内容阅读
[目的]探讨射频消融术治疗局部进展期胰腺癌的临床疗效.[方法]本院收治的123例局部进展期胰腺癌患者,依据其姑息性手术中是否行射频消融术分为射频组和对照组,比较两组患者治疗及预后情况.[结果]123例患者均顺利完成手术,无围手术期死亡患者.射频组患者术后并发症发生率为21.7％(10/46),胰瘘发生率为6.5％(3/46),与对照组10.38％(8/77),1.3％(1/77)相比较差异均无显著性(P＞0.05).射频组患者的半年、1年、2年生存率分为82.6％(38/46)、43.5％(20/46)、8.7％(4/46),平均生存时间为(13.5±0.8)个月;明显高于对照组55.8％(43/77)、27.27％(21/77)、0％和(9.1±0.3)个月,且差异均有显著性(P＜0.05).[结论]射频消融术用于治疗局部进展期胰腺癌安全有效,其为胰腺癌患者的综合治疗提供了一种新的方法.“,”[Objective]To analysis of radiofrequency ablation in the treatment of locally-advanced pancreatic carcinoma.[Methods]We retrospectively analyzed the clinical data of 123 patients with locally-advanced pancreatic carcinoma.All the patients were divided into a radiofrequency group and a control group according to the radiofrequency ablation surgery.And then the perioperative and prognosis data of the two groups were analyzed and compared.[Results]In our research,all patients were successfully completed surgery and there were no cases of perioperative death.The incidence of postoperative complications of radiofrequency group was 21.7％ (control group rate 10.38 ％) and the incidence of pancreatic fistula was 6.5 ％ (control group rate 1.3 ％).There were no statistical differences between the two groups.The 6 months,1 year and 2 years survival rates of radiofrequency group and control group were 82.4％,43.5％,7.6％ and 55.8％,28％,0％,the average survival time were 13.5±0.8 months and 9.1±0.3 months.The prognosis of radiofrequency group was significantly better than that of the control group (P ＜0.05).[Conclusion]Radiofrequency ablation surgery is safe and effective in the treatment of locally-advanced pancreatic carcinoma.