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目的对不同时期介入治疗与药物保守治疗老年不稳定性心绞痛的临床效果进行分析和比较。方法选取医院收治的老年不稳定性心绞痛患者90例为研究对象,随机分为早期观察组、择期观察组、对照组3组,每组30例。早期观察组接受早期经皮冠状动脉介入治疗,择期观察组接受择期经皮冠状动脉介入治疗,对照组接受药物保守治疗。分别于治疗前1 d以及治疗后6个月,检查患者左心室功能;保持随访,记录3组患者治疗期间的心血管事件发生情况;同时统计随访期间3组患者各自的再入院情况,计算再入院发生率。结果治疗后,早期、择期观察组各项左心室功能指标水平均优于对照组(P<0.05),早期、择期观察组患者组间比较差异不显著(P>0.05)。早期观察组和择期观察组心血管事件发生情况及再入院率比较差异均无统计学意义(P>0.05);相较于对照组,早期观察组和择期观察组心肌梗死、心力衰竭率以及再入院率低,出血发生率高(P均<0.05)。结论相较于药物保守治疗,介入治疗在老年不稳定性心绞痛患者中的应用效果更佳;此外,不同时期介入治疗效果相当,实际应用中可依据患者具体情况选择合适的时期进行手术,以实现最佳治疗效果。
Objective To analyze and compare the clinical effects of interventional therapy and drug conservative treatment of senile unstable angina at different periods. Methods Ninety elderly patients with unstable angina pectoris admitted to hospital were enrolled in this study. They were randomly divided into early observation group, elective observation group and control group, with 30 cases in each group. Early observation group received early percutaneous coronary intervention, elective observation group undergoing elective percutaneous coronary intervention, the control group received conservative treatment. Left ventricular function was examined at 1 day before treatment and 6 months after treatment. The patients were followed up and recorded the occurrence of cardiovascular events during the treatment period. At the same time, the readmission of three groups of patients during the follow-up period was calculated. Admission rate. Results After treatment, the indexes of left ventricular function in early and elective observation groups were better than those in control group (P <0.05). There was no significant difference in early and elective observation group between the two groups (P> 0.05). There were no significant differences in the incidence of cardiovascular events and readmission rates between the early observation group and the elective observation group (P> 0.05). Compared with the control group, the incidences of myocardial infarction and heart failure in the early observation group and the elective observation group Low admission rate and high bleeding rate (all P <0.05). Conclusion Compared with drug conservative treatment, interventional therapy is more effective in elderly patients with unstable angina pectoris. In addition, interventional therapy at different periods has the same effect. In practice, surgery can be performed according to the specific conditions of the patients and the appropriate period can be achieved The best treatment.