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近年来,干预NLRP3炎症小体作为治疗非小细胞肺癌的研究新方向渐受重视,大量的研究表明,NLRP3炎症小体不仅是炎症发生的中心环节,也是促进肿瘤形成、侵袭、转移的重要因素。目前已发现多种中药的提取物及化合物对NLRP3炎症小体有抑制作用,文章旨在为中医药干预NLRP3炎症小体的现状及前景在治疗非小细胞肺癌的研究领域进行探讨。
In recent years, intervention NLRP3 inflammasome as a new direction for the treatment of non-small cell lung cancer has been paid more attention, a large number of studies have shown that NLRP3 inflammasome is not only the central part of inflammation, but also promote tumor formation, invasion and metastasis of important factors . It has been found that many Chinese herbal extracts and compounds have inhibitory effects on the NLRP3 inflammasome. The purpose of this article is to explore the status quo and prospect of TCM intervention in the NLRP3 inflammasome in the field of the treatment of non-small cell lung cancer.