本文对65例肾活检中的9例膜增殖性肾小球肾炎(MPGN)超微结构进行了分析,其特点为MPGN-Ⅰ型以内皮下电子致密沉积物为主,MPGN-Ⅱ型以基底膜致密层电子致密沉积物为主,同时在两型中伴有肾小球基底膜不规则增厚,系膜细胞、基质的增多并插入基底膜和内皮细胞之间。结果表明,膜增殖性肾小球肾炎的超微结构在病理学分型、诊断和鉴别诊断中具有重要意义。 In this paper, 9 cases of 65 cases of renal biopsy membranoproliferative glomerulonephritis (MPGN) ultrastructure was analyzed, which is characterized by MPGN-type Ⅰ to subendothelial electron dense sediments, MPGN-Ⅱ type basement membrane Tight dense electron dense sediment, accompanied by two types of glomerular basement membrane irregular thickening, mesangial cells, matrix increased and inserted between the basement membrane and endothelial cells. The results show that the ultrastructure of proliferative glomerulonephritis in the pathological classification, diagnosis and differential diagnosis of great significance.