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目的观察中西医结合治疗慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)急性加重期的临床疗效。方法选取2008年7月—2012年6月住院的COPD急性加重期患者68例,随机分为对照组和治疗组各34例,对照组常规给予控制感染、改善通气、氧疗、止咳化痰、支气管扩张、营养支持、维持水与电解质平衡等综合治疗,且根据患者具体情况和用药反应调整用药方案。治疗组在对照组基础上加服麻杏石甘汤加味,水煎服,日1剂。两组均治疗7 d为1个疗程,共治疗2个疗程。计数资料采用χ2检验,P<0.05为差异有统计学意义。结果总有效率对照组76.5%,治疗组97.1%,比较差异有统计学意义(P<0.05)。结论在常规西医治疗的基础上给予麻杏石甘汤加味治疗COPD可改善气道炎症和微循环,效果满意,值得推广。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in treating acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Sixty-eight patients with acute exacerbation of COPD who were admitted to hospital from July 2008 to June 2012 were randomly divided into control group and control group, with 34 cases in each group. The control group was given routine infection control to improve ventilation, oxygen therapy, relieving cough and resolving phlegm, Bronchiectasis, nutritional support, maintaining water and electrolyte balance and other comprehensive treatment, and according to the specific circumstances of patients and medication regimen adjustment program. On the basis of the control group, the treatment group added Modified Maxing Shigan Decoction, Shuijianbi, a day. Both groups were treated for 7 days for a course of treatment, a total of 2 courses of treatment. Count data using χ2 test, P <0.05 for the difference was statistically significant. Results The total effective rate was 76.5% in the control group and 97.1% in the treatment group, the difference was statistically significant (P <0.05). Conclusion The treatment of COPD with Maxing Shigan Decoction based on routine western medicine can improve airway inflammation and microcirculation with satisfactory results and is worthy of promotion.